Bio-degradable highly fluorescent conjugated polymer nanoparticles for bio-medical imaging applications

Conjugated Polymer Nanoparticles in Bio- Sensing and Bio-Imaging

Development of Convergence Nanoparticles for Multi-Modal Bio-Medical Imaging

Applications of gold nanoparticles for medical imaging

Background & Aim: Molecular imaging enables us to non-invasively visualize tissue microstructures and lesion characterization, allowing accurate diagnosis of diseases at early stages. A successful molecular imaging requires a nontoxic contrast agent with high sensitivity. Nowadays, a wide range of nanoparticles have been developed as contrast agents for medical imaging modalities. Here, we revi...

Breakthroughs in Nanoparticles for Bio-Imaging

Highly emissive PEG-encapsulated conjugated polymer nanoparticles.

A novel bioimaging probe based on a conjugated polymer, poly(9,9-dihexylfluorene-alt-2,1,3-benzoxadiazole) (PFBD), is demonstrated. Transfer of the hydrophobic polymer into water using a short chain poly(ethylene glycol) (PEG) resulted in conjugated polymer nanoparticles (PEG-PFBD) with a fluorescence quantum yield of 46%. The PEG-PFBD nanoparticles possessed several desirable structural and ph...